Which medications in the drug class Penicillins are used in the treatment of Appendicitis?

Updated: Jul 23, 2018
  • Author: Sandy Craig, MD; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
  • Print
Answer

Penicillins

The penicillins are bactericidal antibiotics that work against sensitive organisms at adequate concentrations and inhibit the biosynthesis of cell wall mucopeptide.

Piperacillin and tazobactam sodium (Zosyn)

This agent is a drug combination of beta-lactamase inhibitor with piperacillin. It has activity against some gram-positive organisms, gram-negative organisms, and anaerobic bacteria. When used as a single agent, it inhibits biosynthesis of cell wall mucopeptide and is effective during active multiplication stages.

Ampicillin and sulbactam (Unasyn)

This agent is a drug combination of beta-lactamase inhibitor with ampicillin. It is used as a single agent and interferes with bacterial cell wall synthesis during active replication, causing bactericidal activity against susceptible organisms. Ampicillin/sulbactam also has activity against some gram-positive organisms, gram-negative organisms (nonpseudomonal species), and anaerobic bacteria.

Ticarcillin/clavulanate (Timentin)

Ticarcillin/clavulanate inhibits biosynthesis of cell wall mucopeptide and is effective during the stage of active growth. It is an antipseudomonal penicillin plus beta-lactamase inhibitor that provides coverage against most gram-positive organisms, most gram-negative organisms, and most anaerobic organisms.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!