When are preoperative antibiotics indicated in the treatment of appendicitis?

Updated: Jul 23, 2018
  • Author: Sandy Craig, MD; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Answer

Preoperative antibiotics have demonstrated efficacy in decreasing postoperative wound infection rates in numerous prospective controlled studies, and they should be administered in conjunction with the surgical consultant. Broad-spectrum gram-negative and anaerobic coverage is indicated (see Medication).

Penicillin-allergic patients should avoid beta-lactamase type antibiotics and cephalosporins. Carbapenems are a good option in these patients.

Pregnant patients should receive pregnancy category A or B antibiotics.


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