What is the sensitivity of C-reactive protein level (CRP) in the diagnosis of appendicitis?

Updated: Jul 23, 2018
  • Author: Sandy Craig, MD; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Answer

Multiple studies have examined the sensitivity of CRP level alone for the diagnosis of appendicitis in patients selected to undergo appendectomy. Gurleyik et al noted a CRP sensitivity of 96.6% in 87 of 90 patients with histologically proven disease. [24] Similarly, Shakhetrah found a CRP sensitivity of 95.5% in 85 of 89 patients with histologically proven appendicitis. [25] Asfar et al reported a CRP sensitivity of 93.6% in 78 patients undergoing appendectomy, [26] and Erkasap et al found a CRP sensitivity of 96% in a group of 102 adult patients with right lower quadrant (RLQ) pain, 55 of whom proceeded to appendectomy. [27]


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