What is the role of C-reactive protein (CRP) in the diagnosis of appendicitis?

Updated: Jul 23, 2018
  • Author: Sandy Craig, MD; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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C-reactive protein (CRP) is an acute-phase reactant synthesized by the liver in response to infection or inflammation and rapidly increases within the first 12 hours. CRP has been reported to be useful in the diagnosis of appendicitis; however, it lacks specificity and cannot be used to distinguish between sites of infection.

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