What are the characteristics of the early stage of appendicitis?

Updated: Jul 23, 2018
  • Author: Sandy Craig, MD; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Answer

In the early stage of appendicitis, obstruction of the appendiceal lumen leads to mucosal edema, mucosal ulceration, bacterial diapedesis, appendiceal distention due to accumulated fluid, and increasing intraluminal pressure. The visceral afferent nerve fibers are stimulated, and the patient perceives mild visceral periumbilical or epigastric pain, which usually lasts 4-6 hours.


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