Which antibiotics may be used in the treatment of appendicitis and how are they administered?

Updated: Jul 23, 2018
  • Author: Sandy Craig, MD; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
  • Print


  • Antibiotic prophylaxis should be administered before every appendectomy

  • Preoperative antibiotics should be administered in conjunction with the surgical consultant

  • Broad-spectrum gram-negative and anaerobic coverage is indicated

  • Cefotetan and cefoxitin seem to be the best choices of antibiotics

  • In penicillin-allergic patients, carbapenems are a good option

  • Pregnant patients should receive pregnancy category A or B antibiotics

  • Antibiotic treatment may be stopped when the patient becomes afebrile and the WBC count normalizes

See Treatment and Medication for more detail.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!