What is the role of urinary 5-HIAA levels in the diagnosis of appendicitis?

Updated: Jul 23, 2018
  • Author: Sandy Craig, MD; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Answer

HIAA levels increase significantly in acute appendicitis and decrease when the inflammation shifts to necrosis of the appendix. [6] Therefore, such decrease could be an early warning sign of perforation of the appendix.


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