When are suppressive antibiotics indicated in the treatment of chronic bacterial prostatitis (CBP)?

Updated: May 25, 2021
  • Author: Samantha D Kraemer, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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Patients with persistent or recurrent infections, especially those who have symptom improvement while on antibiotics but who quickly have a recurrence after finishing a course of antibiotics, may benefit from suppressive therapy with low-dose daily prophylactic antibiotics. Clinical studies have not confirmed the value of suppressive therapy in this setting, but it is widely used. [1] Good choices are tetracycline, nitrofurantoin, nalidixic acid, cephalexin, and trimethoprim. Bacteria in CBP are usually sensitive strains, even after a number of antibiotic treatment regimens have been tried.

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