Why are fluoroquinolones the antibiotics of choice for the treatment of chronic bacterial prostatitis (CBP)?

Updated: May 25, 2021
  • Author: Samantha D Kraemer, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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The antibiotics of choice are the fluoroquinolones (eg, ciprofloxacin, levofloxacin, ofloxacin, moxifloxacin), due to their favorable pharmacokinetic properties and broad-spectrum activity. Fluoroquinolones have demonstrated high bactericidal activity against the Enterobacteriaceae group of bacteria and against Pseudomonas aeruginosa. They also have activity against chlamydial and gonococcal organisms. However, fluoroquinolones are generally ineffective against streptococci, enterococci, and anaerobes.

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