What is the diagnostic standard for chronic bacterial prostatitis (CBP)?

Updated: May 25, 2021
  • Author: Samantha D Kraemer, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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For localization of UTI, the four-glass test is still considered the diagnostic standard, but it is cumbersome and has little use in the clinical setting. [2] The two-glass test, also known as pre-massage and post-massage test (originally suggested by Weidner and Ebner in 1985 and supported by Nickel [3, 4] ) is more commonly used, as it is simple and cost-effective.

However, some patients may have bacterial infection despite negative urine cultures. Negative culture results occur for various reasons, including insufficient sample volume, initiation of antibiotics prior to obtaining an EPS sample, and the presence of fastidious organisms. In such cases, patients often have symptom improvement after antibiotic treatment.

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