How does the brain signal bladder fullness in the neuroanatomy of neurogenic bladder?

Updated: Dec 24, 2020
  • Author: Bradley C Gill, MD, MS; Chief Editor: Edward David Kim, MD, FACS  more...
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When the bladder becomes full, the stretch receptors of the detrusor muscle send a signal to the pons, which in turn notifies the brain. People perceive this signal (bladder fullness) as a sudden desire to urinate, or urinary urge. Under normal situations, the brain sends an inhibitory signal to the pons via the periaqueductal gray matter to inhibit the bladder from contracting until a bathroom is found.

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