What is the prevalence of precancerous lesions of the prostate?

Updated: Feb 26, 2020
  • Author: Stanley A Brosman, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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The reported frequency of HGPIN varies from 0.7-20%; the frequency seems to vary with the pathologist and the number of biopsies obtained.

In an analysis of 17 studies, in which a total of 87,713 patients underwent biopsy, 3735 (4.26%) patients had HGPIN. The largest contributors to this total were Orozco et al, [4] with 62,537 patients (of whom 4.1% had HGPIN), and Novis et al, [5] with 15,753 patients (of whom 3.9% had HGPIN).

ASAP lesions have been identified in 0.5-23% of patients undergoing needle biopsies of the prostate.

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