How is MET administered for the treatment of nephrolithiasis?

Updated: Sep 16, 2021
  • Author: Chirag N Dave, MD; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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A typical regimen for this aggressive therapy is as follows:

  • 1-2 oral narcotic/acetaminophen tablets every 4 hours as needed for pain

  • 600-800 mg ibuprofen every 8 hours

MET with 0.4 mg tamsulosin once daily or 4 mg of terazosin once daily is recommended dosing.

Limit MET to a 10- to 14-day course, as most stones that pass during this regimen do so in that time frame. If outpatient treatment fails, promptly consult a urologist.

Future studies may identify a subgroup of patients such as those with larger stones or history of inability to pass stones that would benefit from MET.

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