What are the racial predilections of nephrolithiasis?

Updated: Jan 13, 2020
  • Author: Chirag N Dave, MD; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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Urinary tract calculi are far more common in Asians and Caucasians than in Native Americans, Africans, African Americans, and some natives of the Mediterranean region. Caucasian males are affected 3-4 times more often than African American males, though African Americans have a higher incidence of infected ureteral calculi than Caucasians. With uric acid stones, however, non-Caucasian have a higher frequency of stone formation than Caucasians. Some groups, such as the Hmong, have frequencies up to 50%.{ref80)

Although some differences may be attributable to geography (stones are more common in hot and dry areas) and diet, heredity also appears to be a factor. This is suggested by the finding that, in regions with both Caucasian and non-Caucasian populations, stone disease is much more common in Caucasians.

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