Which lab tests are performed in the workup of nephrolithiasis?

Updated: Jan 13, 2020
  • Author: Chirag N Dave, MD; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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The European Association of Urology (EAU) recommends the following laboratory tests in all patients with an acute stone episode [1] :

  • Urinary sediment/dipstick test: To demonstrate blood cells, with a test for bacteriuria (nitrite) and urine culture in case of a positive reaction

  • Serum creatinine level: To measure renal function

Other laboratory tests that may be helpful include the following:

  • CBC with differential in febrile patients

  • Serum electrolyte assessment in vomiting patients (eg, sodium, potassium, calcium, phosphorus)

  • Serum and urinary pH level: May provide insight regarding patient’s renal function and type of calculus (eg, calcium oxalate, uric acid, cystine), respectively

  • Microscopic urinalysis

  • 24-hour urine profile

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