Which nonspecific findings may affect the accuracy of CT in the diagnosis of ulcerative colitis (UC)?

Updated: Apr 23, 2019
  • Author: Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR; Chief Editor: Eugene C Lin, MD  more...
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Bowel thickening is a nonspecific finding; it may be encountered in a variety of colitides and other pathologies of the bowel wall. The target sign is also nonspecific; it has been reported in Crohn colitis. Mucosal ulceration is difficult to detect with CT.

The target sign may be secondary to a hypoattenuating submucosal layer of fluid (nonspecific) or fat (chronic in origin and usually from IBD). Also, there is evidence that submucosal fat may be a normal variant.

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