What is the role of nuclear imaging in the workup of toxic megacolon?

Updated: Apr 03, 2019
  • Author: Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR; Chief Editor: Eugene C Lin, MD  more...
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Technetium-99m (99mTc) hexamethyl-propyleneamine oxime (HMPAO)–labeled WBC scanning can be used as an alternative to colonoscopy to assess the extent and severity of the disease in critically ill patients with ulcerative colitis. This technique decreases the number and severity of complications that may occur in these patients. However, the role of this method of scintigraphy is limited in the diagnosis of toxic megacolon and in the determination of its severity. [18]

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