Is methotrexate (MTX) safe for breastfeeding women with rheumatoid arthritis (RA)?

Updated: May 11, 2018
  • Author: Katherine K Temprano, MD; Chief Editor: Christine Isaacs, MD  more...
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Methotrexate is excreted in breast milk in low concentrations and can accumulate in neonatal tissues; thus, it is contraindicated during breastfeeding. [53]  Both EULAR and BSR-BHPR guidelines recommend that nursing mothers avoid methotrexate. [18, 19]

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