What is the glucocorticoids regimen for the remission maintenance of granulomatosis with polyangiitis (GPA)?

Updated: Aug 31, 2021
  • Author: Christopher L Tracy, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Prednisone should be tapered to 10 mg/day or less during remission.

The prednisone dose can be tapered gradually after 6-18mo depending on the patient’s response

Recommend baseline evaluation of bone mineral density

Recommend daily calcium and vitamin D supplementation

Recommend consideration of bisphosphonate therapy to prevent glucocorticoid-induced osteoporosis, depending on renal function


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