What is the prevalence of renal disease in granulomatosis with polyangiitis (GPA)?

Updated: Aug 31, 2021
  • Author: Christopher L Tracy, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Renal disease is present in 17% of patients at initial diagnosis and is usually asymptomatic. [4] Renal failure occurs in 11% at presentation. [2] Renal disease manifests as crescentic necrotizing glomerulonephritis characterized by urinary sediment with more than 5 red blood cells per high-power field or erythrocyte casts.


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