Which patient groups have the highest prevalence of granulomatosis with polyangiitis (GPA)?

Updated: Aug 31, 2021
  • Author: Christopher L Tracy, MD; Chief Editor: Herbert S Diamond, MD  more...
  • Print

GPA is more common in individuals of northern European descent (approximately 90%); it occurs less commonly in blacks.

In European populations, GPA is slightly more common in men, with a male-to-female ratio of 1.5:1. [34] Women are more likely to have limited disease. [12]

The onset of GPA may occur at any age, although patients typically present at age 35-55 years. GPA is rare in childhood. [35] In a systematic review and meta-analysis of childhood-onset GPA, the age range was 4-18 years. The majority of patients were adolescent girls. [36]

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!