What are the ENT signs and symptoms of granulomatosis with polyangiitis (GPA)?

Updated: Aug 31, 2021
  • Author: Christopher L Tracy, MD; Chief Editor: Herbert S Diamond, MD  more...
  • Print

Chronic sinusitis is the most common initial complaint in GPA, occurring in 67% of cases; failure to respond to conventional treatment is suggestive. Other ENT manifestations are as follows:

  • Rhinitis (22%) [2]

  • Epistaxis (11%) [2]

  • Collapse of nasal support, resulting in saddle nose deformity (common)

  • Serous otitis media and hearing loss

  • So-called strawberry gingival hyperplasia

  • Stridor, possibly leading to respiratory compromise, from tracheal or subglottic granulomatous masses

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!