Which medications in the drug class Gastrointestinal Agents, Other are used in the treatment of Sjogren Syndrome?

Updated: Mar 05, 2021
  • Author: Sriya K Ranatunga, MD, MPH; Chief Editor: Herbert S Diamond, MD  more...
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Gastrointestinal Agents, Other

These agents bind to cholinergic (muscarinic) receptors, increasing the secretion of exocrine glands, including salivary glands.

Pilocarpine (Salagen)

Pilocarpine is a cholinergic parasympathomimetic agent that can be used to enhance secretion by exocrine glands when systemic therapy is needed or local therapy fails.

Artificial saliva

These preparations typically contain methylcellulose, sorbitol, and salts to moisten and lubricate the mouth.

Cevimeline (Evoxac)

Cevimeline is indicated for xerostomia in Sjögren syndrome.

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