Which medications in the drug class Antineoplastics, Alkylating are used in the treatment of Sjogren Syndrome?

Updated: Mar 05, 2021
  • Author: Sriya K Ranatunga, MD, MPH; Chief Editor: Herbert S Diamond, MD  more...
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Antineoplastics, Alkylating

Consider these agents in patients with Sjögren syndrome who develop a major organ manifestation such as interstitial lung disease.

Cyclophosphamide (Cytoxan)

Cyclophosphamide is an alkylating agent with potent immunosuppressant properties. Dosage adjustments should be based on monitoring clinical response and the CBC or nadir CBC.

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