For which systemic manifestations of Sjögren syndrome should treatment with rituximab be considered?

Updated: Mar 05, 2021
  • Author: Sriya K Ranatunga, MD, MPH; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Rituximab may be considered as a therapeutic option for adults with primary Sjögren syndrome and any or all of the following systemic manifestations:

  • Cryoglobulinemia associated with vasculitis
  • Vasculitis
  • Severe parotid swelling
  •  Inflammatory arthritis
  • Pulmonary disease
  • Peripheral neuropathy, especially mononeuritis

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