What are the Sjögren’s Syndrome Foundation (SSF) treatment guidelines for dry mouth in Sjögren syndrome?

Updated: Mar 05, 2021
  • Author: Sriya K Ranatunga, MD, MPH; Chief Editor: Herbert S Diamond, MD  more...
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Recommendations (and their strength) for Sjögren syndrome patients with dry mouth include the following:

  • Topical fluoride should be used in for caries prophylaxis (strong)
  • Saliva can be increased through gustatory, masticatory stimulation, sugar-free lozenges and/or chewing gum, xylitol, mannitol, and the prescription medications pilocarpine and cevimeline (weak)
  • Chlorhexidine administered by varnish, gel, or rinse may be considered in patients with a high root caries rate (weak)
  • Nonfluoride remineralizing agents may be considered as an adjunct therapy in patients with a high root caries rate (moderate)

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