How is eosinophilic fasciitis (EF) treated?

Updated: Dec 24, 2020
  • Author: Peter M Henning, DO; Chief Editor: Herbert S Diamond, MD  more...
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First-line therapy for eosinophilic fasciitis is with systemic corticosteroids. [6] Although patients may require prolonged therapy, it should be noted that up to one third of eosinophilic fasciitis cases may spontaneously resolve. [58]

Case reports describe the use of a number of agents for second-line therapy. No consensus exists on which agent is best for that purpose.

Physical therapy should be initiated to improve joint mobility and to decrease contractures.Surgical release has been used in some cases to manage significant joint contractures. [59]

Dermatologists, rheumatologists, and surgeons (for the skin-muscle biopsy) are consulted most often for management of these cases.

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