How are neuroplastic changes used in the rehabilitation of middle cerebral artery (MCA) stroke?

Updated: Mar 17, 2020
  • Author: Daniel I Slater, MD; Chief Editor: Stephen Kishner, MD, MHA  more...
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Neuroplastic changes have been fostered through traditional therapy, pharmaceutical therapy, and modality-based interventions. The changes are then observed with methods showing new synaptogenesis, as well as alterations in genetic expression, functional imaging, and evoked potential activity. Individualized therapy may someday rely on careful observation of impairment and functional disability, as well as on information derived from these sophisticated means of directly observing cortical activity and change. Currently, such endeavors are cost prohibitive, and use of basic science is largely reserved for academic research centers. However, these applications show potential to help even those with chronic impairment, well beyond what was formerly thought feasible in functional recovery. [4, 23]

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