Which medications are used in the treatment of autonomic dysreflexia?

Updated: Mar 02, 2020
  • Author: Ryan O Stephenson, DO; Chief Editor: Milton J Klein, DO, MBA  more...
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Answer

The most commonly used agents are nifedipine and nitrates (eg, nitroglycerine paste or sublingual nitroglycerine). [27] Nifedipine should be in the immediate-release form; bite and swallow is the preferred method of administering the drug, not sublingual administration. Other agents used are prazosin, captopril, terazosin, mecamylamine, diazoxide, and phenoxybenzamine. Use antihypertensives with extreme caution in older persons or in people with coronary artery disease. Note that men with spinal cord injury often use cGMP-specific phosphodiesterase type 5 (PDE5) inhibitors (eg, sildenafil, vardenafil, tadalafil.) for sexual dysfunction. Use of nitrates is contraindicated in this situation.


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