How is thromboembolism prevented in patients with Guillain-Barre syndrome (GBS)?

Updated: Jul 14, 2021
  • Author: Michael T Andary, MD, MS; Chief Editor: Milton J Klein, DO, MBA  more...
  • Print

Venous thromboembolism is one of the major sequelae of extremity paralysis. Time to development of DVT or pulmonary embolism varies from 4-67 days following symptom onset. [3] Prophylaxis with gradient compression hose and subcutaneous LMWH may dramatically reduce the incidence of venous thromboembolism. [3]

True gradient compression stockings (30-40 mm Hg or higher) are highly elastic and provide compression along a gradient that is highest at the toes and gradually decreases to the level of the thigh. This reduces capacity venous volume by approximately 70% and increases the measured velocity of blood flow in the deep veins by a factor of 5 or more.

The ubiquitous white stockings known as antiembolic stockings or thromboembolic disease (TED) hose produce a maximum compression of 18 mm Hg and rarely are fitted in such a way as to provide adequate gradient compression. They have not been shown to be effective as prophylaxis against thromboembolism.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!