How effective is plasma exchange in the treatment of Guillain-Barre syndrome (GBS)?

Updated: Jul 14, 2021
  • Author: Michael T Andary, MD, MS; Chief Editor: Milton J Klein, DO, MBA  more...
  • Print

Plasma exchange carried out over a 10-day period may aid in removing autoantibodies, immune complexes, and cytotoxic constituents from serum and has been shown to decrease recovery time by 50%. A review of 6 randomized, controlled trials involving 649 participants found that plasma exchange helped speed recovery from GBS without causing harm, apart from being followed by a slightly increased risk of relapse. [125]

In well-controlled clinical trials, the efficacy of IVIGs in GBS patients has been shown to equal that of plasma exchange. [126, 127, 128, 129, 130, 131, 132, 133, 134]

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!