Which treatments for Guillain-Barre syndrome (GBS) are administered in the ICU?

Updated: Jul 14, 2021
  • Author: Michael T Andary, MD, MS; Chief Editor: Milton J Klein, DO, MBA  more...
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Good supportive care is critical in the treatment of patients with GBS. [93] Admission to the ICU should be considered for all patients with labile dysautonomia, a forced vital capacity of less than 20 mL/kg, or severe bulbar palsy. [3, 4] Any patients exhibiting clinical signs of respiratory compromise to any degree also should be admitted to an ICU. [3]

Because most deaths related to GBS are associated with complications of ventilatory failure and autonomic dysfunction, many patients need to be monitored closely in ICUs by physicians experienced in acute neuromuscular paralysis and its accompanying complications.

Competent intensive care includes the following features:

  • Respiratory therapy

  • Cardiac monitoring

  • Safe nutritional supplementation

  • Monitoring for infectious complications (eg, pneumonia, urinary tract infections, septicemia)

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