What is the incidence of autonomic dysfunction in Guillain-Barre syndrome (GBS)?

Updated: Jul 14, 2021
  • Author: Michael T Andary, MD, MS; Chief Editor: Milton J Klein, DO, MBA  more...
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A study by Anandan et al indicated that in hospitalized patients with GBS, autonomic dysfunction most frequently manifests as diarrhea/constipation (15.5%), hyponatremia (14.9%), syndrome of inappropriate antidiuretic hormone secretion (SIADH, 4.8%), bradycardia (4.7%), and urinary retention (3.9%). The study included 2587 patients with GBS and 10,348 controls. [107]

Dysautonomia is more frequent in patients with severe weakness and respiratory failure. Autonomic changes rarely persist in a patient with GBS.

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