Does Guillain-Barre syndrome (GBS) negatively affect psychosocial status?

Updated: Jul 14, 2021
  • Author: Michael T Andary, MD, MS; Chief Editor: Milton J Klein, DO, MBA  more...
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GBS can produce long-lasting changes in the psychosocial status of patients and their families. [96, 97, 98] Changes in work and leisure activities can be observed in just over one third of these patients, and psychosocial functional health status can be impaired even years after the GBS event.

Interestingly, psychosocial performance does not seem to correlate with the severity of residual problems with physical function. Poor conditioning and easy fatigability may be contributory factors.

Rudolph et al determined that patients who have had GBS seem overall to have a reduced quality of life and physical functioning. Their findings were based on a study of 42 GBS patients who were examined after a median of 6 years post ̶ disease onset using a variety of measures, including the visual analogue scale (VAS) for pain, the disability rating index (DRI), and the Medical Outcome Study 36-item short-form health status scale (SF-36). [90]

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