What is the incidence of Guillain-Barre syndrome (GBS) in the US?

Updated: Jul 14, 2021
  • Author: Michael T Andary, MD, MS; Chief Editor: Milton J Klein, DO, MBA  more...
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The annual US incidence of GBS is 1.2-3 per 100,000 inhabitants, making GBS the most common cause of acute flaccid paralysis in the United States. [8, 1, 38, 77] In comparing age groups, the annual mean rate of hospitalizations in the United States related to GBS increases with age, being 1.5 cases per 100,000 population in persons aged less than 15 years and peaking at 8.6 cases per 100,000 population in persons aged 70-79 years. [78]

US military personnel are at slightly increased risk of GBS compared with the general population. An antecedent episode of infectious gastroenteritis was a significant risk factor for the development of GBS among military personnel. [24]

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