How are fasciculation treated in amyotrophic lateral sclerosis (ALS)?

Updated: Jan 02, 2020
  • Author: Divakara Kedlaya, MBBS; Chief Editor: Ryan O Stephenson, DO  more...
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Answer

Answer

Fasciculations can be a very early marker of ALS and portend motor unit instability or reinnervation, consistent with a very early phase of increased axonal excitability. [30] Fasciculations can be troublesome or even embarrassing for some patients. Avoiding caffeine and nicotine can reduce them, but in those patients with severe symptoms, benzodiazepines can be effective. Use these medications with caution because of their adverse effect profile.


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