What are the initial ventilator settings in mechanical ventilation?

Updated: Sep 15, 2020
  • Author: Christopher D Jackson, MD; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Initial settings for ventilation may be summarized as follows:

  • Assist-control mode

  • Tidal volume set depending on lung status - Normal = 12 mL/kg ideal body weight; COPD = 10 mL/kg ideal body weight; ARDS = 6-8 mL/kg ideal body weight

  • Rate of 10-12 breaths per minute

  • FIO2 of 100%

  • Sighs rarely needed

  • PEEP only as indicated after first arterial blood gas determination, ie, shunt greater than 25%

  • Inability to oxygenate with an FIO2 less than 60%

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