What is the role of tumor necrosis factor (TNF)–inhibitor therapy in the treatment of sarcoidosis?

Updated: Sep 15, 2020
  • Author: Nader Kamangar, MD, FACP, FCCP, FCCM; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Answer

Callejas-Rubio et al reported inconsistent results with tumor necrosis factor (TNF)–inhibitor therapy. [63] However, at least one study has shown treatment with adalimumab can reduce disease activity, as assessed by fluorodeoxyglucose positron emission tomography (FDG-PET) scanning. [64] Adalimumab has also been used successfully in sarcoidosis patients with refractory chronic noninfectious uveitis. [65]


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