What are the IWOS diagnostic criteria for ocular sarcoidosis?

Updated: Sep 15, 2020
  • Author: Nader Kamangar, MD, FACP, FCCP, FCCM; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Answer

International criteria for the diagnosis of ocular sarcoidosis have been determined from the results of the first International Workshop On Ocular Sarcoidosis. [32] Four levels of certainty for the diagnosis of ocular sarcoidosis (diagnostic criteria) are recommended in patients in whom other possible causes of uveitis had been excluded. Criteria are as follows:

  • Biopsy-supported diagnosis with a compatible uveitis was labeled as definite ocular sarcoidosis

  • If biopsy was not performed but chest the radiograph was positive, showing bilateral hilar lymphadenopathy (BHL) associated with a compatible uveitis, the condition was labeled as presumed ocular sarcoidosis

  • If biopsy was not performed and the chest radiograph did not show BHL but there were 3 intraocular signs and 2 positive laboratory tests, the condition was labeled as probable ocular sarcoidosis

  • If lung biopsy was performed and the result was negative but at least 4 signs and 2 positive laboratory investigations were present, the condition was labeled as possible ocular sarcoidosis


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