What is the role of pulmonary function and carbon monoxide diffusion capacity testing in the workup of sarcoidosis?

Updated: Sep 15, 2020
  • Author: Nader Kamangar, MD, FACP, FCCP, FCCM; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Answer

Pulmonary function tests and a carbon monoxide diffusion capacity test of the lungs for carbon monoxide (DLCO) are used routinely in evaluation and follow-up. Possible findings are as follows:

  • An isolated decrease in DLCO is the most common abnormality

  • A restrictive pattern is seen in patients with more advanced pulmonary disease

  • Approximately 15-20% of patients have obstruction


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