What are in-patient treatment options for fungal pneumonia?

Updated: Jun 21, 2019
  • Author: Romeo A Mandanas, MD, FACP; Chief Editor: Guy W Soo Hoo, MD, MPH  more...
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Watch for rapidly progressive respiratory failure in patients who are neutropenic. Patients may require intubation and mechanical ventilatory support. In patients who are severely neutropenic, rapid progression of fungal pneumonia and dissemination of fungal infection (eg, aspergillosis, mucormycosis) necessitate a high degree of suspicion, early empiric antifungal therapy, and corrective measures (if possible) to reverse neutropenia or other causes of immunosuppression. [5]

Consider rapidly reducing or withdrawing immunosuppressive therapy (eg, corticosteroids), if feasible.

Correct hyperglycemia and acidosis.

Consider the correction of neutropenia via the administration of growth factors (eg, filgrastim [Neupogen], pegfilgrastim [Neulasta], sargramostim [Leukine]) or granulocyte transfusions.

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