Is sublingual immunotherapy (SLIT) proven to improve symptoms of asthma?

Updated: Nov 20, 2020
  • Author: Michael J Morris, MD, FACP, FCCP; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Sublingual immunotherapy (SLIT) has been shown to improve allergic rhinitis symptoms, including in pediatric patients and allergic asthma. While adverse reactions do occur, SLIT is safe enough for home administration. Based on limited data, sublingual therapy, at least in the short term, may be about half as effective as traditional subcutaneous injection. While SLIT is widely used in European, South American, and Asian countries, as of early 2016, it is not FDA approved and remains off-label use in the United States.

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