When is immunotherapy indicated in the treatment of asthma?

Updated: Nov 20, 2020
  • Author: Michael J Morris, MD, FACP, FCCP; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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The use of immunotherapy for the treatment of asthma is controversial. Several large, well-conducted studies did not demonstrate any benefit, but a meta-analysis of 75 randomized controlled trials confirmed efficacy in asthma. [78] The National Asthma Education and Prevention Program Expert Panel Report recommends that immunotherapy be considered if the following criteria are fulfilled:

  • A relationship is clear between symptoms and exposure to an unavoidable allergen to which the patient is sensitive.

  • Symptoms occur all year or during a major portion of the year.

  • Symptoms are difficult to control with pharmacologic management because the medication is ineffective, multiple medications are required, or the patient is not accepting of medication.

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