How do outcomes with oral appliance (OA) therapy compare with nasal continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea (OSA)?

Updated: Sep 15, 2020
  • Author: Himanshu Wickramasinghe, MD, MBBS; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Subsequent prospective controlled clinical trials to compare OA therapy with nasal CPAP therapy to treat OSA and snoring demonstrated the following results:

  • Treatment was successful in 55% of patients using an adjustable mandibular repositioner and in 48% of patients using a nonadjustable mandibular repositioner; treatment success was defined as a posttreatment RDI of less than or equal to 10, with symptomatic relief

  • CPAP therapy was superior to mandibular repositioning in normalizing the RDI, reducing snoring, and improving oxygenation

  • CPAP and adjustable mandibular repositioning equally improved daytime sleepiness

  • Most patients preferred mandibular repositioning therapy to CPAP therapy

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