Which biochemical factors are responsible for the effectiveness of oral appliances (OAs) in obstructive sleep apnea (OSA)?

Updated: Sep 15, 2020
  • Author: Himanshu Wickramasinghe, MD, MBBS; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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The biomechanical factors responsible for the effectiveness of OAs are not completely understood. Increased tone of UA musculature is thought to be the predominant influence on the caliber and volume of the airway. Key among these muscles is the genioglossus muscle. When the jaw is opened, the genioglossus (with other muscles in the pharyngeal airway) influences the airway to improve its caliber and stability.

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