What is the role of testosterone in the etiology of menopausal depression?

Updated: Jan 30, 2019
  • Author: Nita V Bhatt, MD, MPH; Chief Editor: Ana Hategan, MD, FRCPC  more...
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Research has shown that reproductive hormones produced during menopause contribute to mood alterations, such as depression. [11] Higher testosterone levels may directly lead to higher depressive symptoms during the menopausal transition. Menopausal status, however, remains an independent predictor of depressive symptoms. [12]

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