What is the pathology of attention deficit/hyperactivity disorder (ADHD)?

Updated: Oct 01, 2019
  • Author: Stephen Soreff, MD; Chief Editor: Glen L Xiong, MD  more...
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Answer

The pathology of ADHD is not clear. Psychostimulants (which facilitate dopamine release) and noradrenergic tricyclics used to treat this condition have led to speculation that certain brain areas related to attention are deficient in neural transmission. PET scan imaging indicates that methylphenidate acts to increase dopamine. [2] The neurotransmitters dopamine and norepinephrine have been associated with ADHD.


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