What are the prognostic factors of renal transitional cell carcinoma?

Updated: Nov 05, 2019
  • Author: Bagi RP Jana, MD, MBA, MHA, FACP; Chief Editor: E Jason Abel, MD  more...
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Answer

The prognosis is poor for patients with advanced SCC.

Vecchi et al have developed and validated two nomograms for predicting overall survival in patients with metastatic UC. The nomograms are intended to be used before and after completion of first-line platinum-based chemotherapy for metastatic UC. [9]

Adverse prognostic factors in patients receiving salvage systemic therapy for advanced UC include the following [10] :

  • Eastern Cooperative Oncology Group (ECOG) performance status >0
  • Liver metastasis
  • Hemoglobin level < 10 g/dL
  • < 3 months since prior chemotherapy
  • Albumin level below the lower limit of normal [11]

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