What are the symptoms of estrogen deficiency during menopausal transition?

Updated: Oct 16, 2018
  • Author: Janice L Bacon, MD; Chief Editor: Richard Scott Lucidi, MD, FACOG  more...
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During the menopausal transition, a reduction in ovarian function results in a number of symptoms. Symptoms secondary to changes in ovarian hormones can be difficult to distinguish from those due to general aging and/or other medical or endocrine disorders.

Many symptoms are attributed to estrogen deficiency and they vary in intensity among women. Symptoms most commonly reported during the menopausal transition include vasomotor symptoms, such as hot flashes and night sweats, and sleep disturbances. [110]

The prevalence of vasomotor symptoms is 14-51% in premenopausal women, 35-50% in perimenopausal women, a 30-80% in postmenopausal women. [1] Most women have hot flashes for 6 months to 2 years. However, one study group reported that 26% of women had hot flashes for 6-10 years and that 10% had them for more than 10 years. [13]

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