What is the role of endometrial sampling in the pretreatment evaluation for menopausal hormone replacement therapy (HRT)?

Updated: Sep 13, 2021
  • Author: Nicole K Banks, MD; Chief Editor: Richard Scott Lucidi, MD, FACOG  more...
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Endometrial sampling: This test is not required in routine practice. If abnormal bleeding is present before or during HT, ultrasonography is recommended to check endometrial thickness (cutoff, < 4 mm), followed by outpatient Pipelle sampling and hysteroscopy. In patients with a tight cervix, formal hysteroscopy and dilation and curettage under general anesthesia are advised.

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